How to use Nicotinell™ patches 1.The patch can be usedfor 24 hours 2. Place the patch in the right place We recommend that you use Nicotinell™ nicotine patches around the clock and put on a new patch every morning when you remove the old one. You can use the patch on your upper arm, upper back or hip. Ensure that your skin is unbroken, dry and hair-free. Smooth out the edges of the patch to ensure that it adheres properly. Choose a new spot every day and do not use the same spot again for at least seven days. When the patch is adhered to your skin, it releases nicotine. Nicotine can irritate your skin, so you may notice red marks when you remove the patch. The redness usually disappears after a few days and is not dangerous. If your skin feels itchy or if you notice blisters forming, then you should stop using the patch immediately, since this can indicate an allergic reaction to the nicotine or the adhesive. Please read the leaflet enclosed in the pack and make sure you follow the instructions carefully. Combination Therapy Combination therapy is when you use more than one nicotine replacement product at once, e.g. nicotine patches to help control cravings 24/7, and gum for extra strong urges. If you’re a heavy smoker or have failed to quit using one product before, combination therapy might be for you.With two treatments, you can manage craving around the clock. Make sure you talk to a healthcare professional before you start.